Which rescue drug is administered to reverse the effects of opioids?

Naloxone is the correct choice for reversing the effects of opioids because it is specifically designed to bind to the same receptors in the brain that opioids do. When administered, Naloxone displaces the opioid molecules from these receptors, thereby rapidly reversing opioid overdose symptoms such as respiratory depression and sedation. This makes it a critical medication in emergency situations where someone has overdosed on opioids, allowing for rapid intervention.

Though other options, such as Naltrexone and Buprenorphine, are also related to opioid treatment, they serve different purposes. Naltrexone is used in the long-term management of opioid dependence rather than for acute reversal of overdose. Buprenorphine is a partial agonist that can mitigate cravings and withdrawal symptoms but is not intended for emergency reversal of acute opioid effects. Methadone is primarily used as a maintenance treatment for opioid dependence and does not reverse overdose effects.

Understanding Naloxone's specific role in emergency medical settings emphasizes its importance in saving lives during an opioid overdose, distinguishing it clearly as the essential rescue drug for this purpose.